TB Research

Active Pulmonary Tuberculosis During Interferon Beta-1a Therapy in a Child with Multiple Sclerosis: A Case Report

Pakize Cennetoğlu, Zeynep Öz, Canan Caymaz, Peren Perk Yücel, Pınar Arıcan, İhsan Kafadar

Cam and Sakura Medical Journal · 2023-01

Abstract

Beta interferons are the first class of disease-modifying therapies, and their immunomodulatory effects are achieved by inhibiting T-cell activation and proliferation. However, modulation and interference with the patient's immune system may lead to adverse effects, such as increased susceptibility to infections.

MeSH terms

  • Multiple sclerosis
  • Medicine
  • Interferon beta-1b
  • Interferon beta
  • BETA (programming language)
  • Tuberculosis
  • Pulmonary tuberculosis
  • Immunology
  • Pediatrics