Trends and Perspectives in Tuberculosis and HIV Co-Infection Studies Over the Past Three Decades

Aim: The aim of this study was to analyze and identify the status, hot spots and frontiers of HIV- Mycobacterium tuberculosis (MTB) research using CiteSpace. Method: We searched the Web of Science Core Collection. The publications were visually analyzed in terms of countries, institutions, authors, keywords, references, and journals using CiteSpace. Results: A total of 6446 HIV-MTB-related publications were retrieved. The top three keywords with the highest frequency were Mycobacterium tuberculosis, HIV, and infection. Conclusion: In recent years, research hotspots have mainly focused on the epidemiology, immune mechanisms, prevention and treatment of HIV-MTB co-infection, especially regarding immune response, burden, assays, latent TB, and children co-infected with AIDS and TB. They need to be addressed in future studies.