TB Research

[Thoracic Endovascular Aortic Repair for Mycotic Thoracic Aortic Aneurysm After BCG Intravesical Therapy].

Hayato Obi, Kanetsugu Nagao, Masaya Aoki, Saori Nagura, Shigeyuki Yamashita, Toshio Doi, Akio Yamashita, Kazuaki Fukahara, et al. (10 authors)

PubMed · 2023-12

Abstract

Bacille Calmette-Guérin( BCG) intravesical therapy is an effective and safe treatment for bladder cancer; however, mycotic aneurysms have been reported as a rare complication. Case 1:A 64-year-old man with a history of BCG intravesical therapy underwent emergent thoracic endovascular aortic repair (TEVAR) for a ruptured thoracic aortic aneurysm (TAA). He was diagnosed with BCG infection by hemosputum specimen culture five months later;then, antituberculous therapy was initiated. However, his follow-up computed tomography scan revealed stent-graft infection and new aneurysm formation. Therefore, we performed a repeated TEVAR with abdominal 4-vessel debranching. There was no recurrence of infection for six years while continuing postoperative antituberculous therapy. Case 2:A 72-year-old man who had undergone BCG intravesical therapy underwent TEVAR for a rapidly enlarging mycotic TAA. He received anti-tuberculous therapy for one year with no recurrent infection for one year. TEVAR may be an effective alternative to the open surgical procedure;however, multidisciplinary treatment including anti-tuberculous therapy and careful long-term follow up are required.

MeSH terms

  • Medicine
  • Surgery
  • Thoracic aortic aneurysm
  • Cardiothoracic surgery
  • Stent
  • Mycotic aneurysm
  • Complication
  • Aneurysm
  • Tuberculosis
  • Radiology
  • Aortic aneurysm