TB Research

Overview: The Challenges Involved with Tuberculosis (TB) Treatment based on Nanotechnology and its Impact on Quality of Life

Yash Srivastav, Akhandnath Prajapati, Madhaw Kumar

International Journal of Pharmaceutical Sciences Review and Research · 2023-10

Abstract

A third of the world's population is thought to be latently infected with Mycobacterium tuberculosis and in danger of the disease reactivating, making TB a highly contagious chronic disease.TB poses a burden for public health because of its high incidence, morbidity, and death in recent decades, where the sanitary emergency has been since.The prevalence of tuberculosis in India is estimated to be 5.05 per 1,000 persons across all subtypes, with 2.27 per 1,000 cases being smear-positive and an annual average of 84 smear-positive cases per 100,000 people.By exploiting immune-mediated lung damage in individuals with active disease, Mycobacterium TB has developed an incredibly efficient aerosol transmission technique.The size of this reaction is reflected by the estimate that one-third of the world's population has developed one.An antigen-specific T-cell response in exposed contacts can be utilised to determine successful transmission.About one in ten individuals in this infected community get active tuberculosis (TB), often a few years after exposure, although continuing to have a lifetime risk of contracting the illness.To create new approaches and delivery systems for the diagnosis and treatment of diseases as well as to improve the qualities of already created systems, nanotechnology can comprehensively examine and utilise innovative elements and properties of materials.Interestingly, nanotechnology could improve and promote the use of innovative drug/antigen delivery systems by fusing and integrating the most recent knowledge of nanomaterials with the understanding of various biological processes.The alternative TB therapy, challenges, and quality of life are all covered in this review paper.

MeSH terms

  • Tuberculosis
  • Nanotechnology
  • Quality (philosophy)
  • Medicine