Recent progress in the genotyping of bovine tuberculosis and its rapid diagnosis <i>via</i> nanoparticle-based electrochemical biosensors
Moustafa Zahran, Rehan M. El-Shabasy, Alyaa Elrashedy, Walid Mousa, Mohamed Nayel, Akram Salama, Ahmed Zaghawa, Ahmed Elsify
RSC Advances · 2023-01
Abstract
and explain the evolutionary and phylogenetic relationships between isolates. The control of bTB disease has attracted a large amount of attention. Rapid and proper diagnosis is necessary for monitoring the disease as an initial step for its control and treatment. Nanotechnology has a potential impact on the rapid diagnosis and treatment of bTB through the use of nanocarrier and metal nanoparticles (NPs). Special attention has been paid to voltammetric and impedimetric electrochemical strategies as facile, sensitive, and selective methods for the efficient detection of tuberculosis. The efficacy of these sensors is enhanced in the presence of NPs, which act as recognition and/or redox probes. Gold, silver, copper, cobalt, graphene, and magnetic NPs, as well as polypyrrole nanowires and multiwalled carbon nanotubes have been employed for detecting tuberculosis. Overall, NP-based electrochemical sensors represent a promising tool for the diagnosis of bTB.
MeSH terms
- Genotyping
- Biosensor
- Nanotechnology
- Nanoparticle
- Tuberculosis
- Computational biology
- Chemistry
- Combinatorial chemistry