TB Research

CLINICAL AND RADIOLOGICAL FEATURES OF PULMONARY TB IN SMOKERS

N.V. Chumovatov, N. S. Antonov, G. M. Sakharova, V. V. Romanov, О. Г. Комиссарова, А. Э. Эргешов

Вестник ЦНИИТ · 2023-01

Abstract

Tobacco use is widely spread all around the world and, according to the World Health Organization, has become the leading cause of death among persons aged ≥ 30 years old. Smoking contributes to the development of many infectious diseases, including pulmonary tuberculosis (TB). Year after year we observe more evidence of the association between long-term smoking and risks for the development of pulmonary TB. Objective: to study the clinical and radiological features into two groups. Group 1 included 63 active smokers, and group 2 included 25 never-smokers. Results. The analysis of the two groups revealed that retreatment and relapse cases were more common among smokers. The majority of newly diagnosed TB cases were among never-smokers. Fibrocavernous pulmonary TB was oftener diagnosed among smokers vs non-smokers. Cavities and sputum positivity was more common among smokers. The analysis of drug resistance patterns established the predominance of MDR and XDR among smokers, while TB in non-smokers was more commonly caused by drug sensitive mycobacteria.

MeSH terms

  • Medicine
  • Sputum
  • Radiological weapon
  • Tuberculosis
  • Pulmonary tuberculosis
  • Internal medicine
  • Drug resistance
  • Cigarette smoking
  • Pediatrics