Author response: Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis
Somnath Shee, Reshma T Veetil, Karthikeyan Mohanraj, Mayashree Das, Nitish Malhotra, Devleena Bandopadhyay, Hussain Beig, Shalini Birua, et al. (19 authors)
Abstract
Genome-scale integration of transposon mutagenesis with a redox biosensor identified a hypothetical transcription factor- Rv0158 required to calibrate the growth, cytoplasmic redox potential, and respiration of Mycobacterium tuberculosis in response to metabolic switching from glucose to fatty acids.
MeSH terms
- Mycobacterium tuberculosis
- Transposon mutagenesis
- Mutagenesis
- Transposable element
- Tuberculosis
- Biology
- Computational biology
- Genetics