TB Research

Tuberculosis Presenting as Ruptured Liver Abscess and Inferior Vena Cava Thrombosis in a Pediatric Patient

Nadia Nazir Jatoi, Marium Ashraf, Varisha Fatima Shaikh, Sharmeen Nasir, Hafsa Nazir Jatoi

Ochsner Journal · 2023-01

Abstract

<h3></h3> <b>Background:</b> Tuberculosis is a leading cause of mortality and morbidity in many countries across the world, including Pakistan. While systemic tuberculosis can involve any organ of the body, tubercular liver abscess is a rare presentation. <b>Case Report:</b> We report the case of an 8-year-old female from a developing country where tuberculosis poses a significant burden on the health care system. The patient presented with fever and weight loss for 6 months and abdominal pain for 14 days. On examination, she had tenderness and guarding over the right hypochondrium. Investigations revealed neutrophilic predominance in the complete blood count and elevated C-reactive protein. Imaging of the abdomen revealed ruptured liver abscess, extensive abdominal lymphadenopathy, and thrombus in the inferior vena cava. Gastric secretions were positive for <i>Mycobacterium tuberculosis</i>. Treatment included antitubercular and antithrombotic therapy. The patient was closely followed until she had completed the 1-year course of antitubercular therapy and was symptom-free. <b>Conclusion:</b> In tuberculosis-endemic countries, physicians should keep a high index of suspicion for tuberculosis in children who present with liver abscess and multisystem involvement.

MeSH terms

  • Medicine
  • Tuberculosis
  • Inferior vena cava
  • Abscess
  • Surgery
  • Liver abscess
  • Abdominal pain
  • Mycobacterium tuberculosis
  • Abdomen
  • Thrombus