Research Capstone Experiences: Design, Synthesis, In Silico Analysis, and Assay Development Towards Prokaryotic Proteasome Antagonists
Tony D. Davis, Serena Farnell, Joseph D'Antonio, Juhi Gurtata, Eric Kelly, Mana Halaji Dezfuli, Azim Sama
American Journal of Pharmaceutical Education · 2023-08
Abstract
Herein, we report the development of antagonists of the Mycobacterium tuberculosis prokaryotic proteasome system (PPS) to address drug-resistant tuberculosis infections.
MeSH terms
- Proteasome
- In silico
- Mycobacterium tuberculosis
- Tuberculosis
- Computational biology
- Drug development
- Biology
- Microbiology
- Drug
- Medicine