Assessment of Lipid Profile on Patients with Pulmonary Tuberculosis

Tuberculosis is one of the first most common causes of deaths in the world alongside HIV/AIDS, causing more than 9.6 million new cases and 1.5 million deaths globally in 2014 alone.This infection also accompanied by lipid profile alterations.The lipid alteration related to the disease is not yet well determined and has variation in different studies.The present study was conducted with the objective to find out lipid profile in newly diagnosed tuberculosis patients.This study aimed at evaluating the lipid profiles in pulmonary tuberculosis patients.A total of eighty (80) subjects were recruited for this study which consists of forty (40) patients with pulmonary tuberculosis out of which twenty (20) were new cases, ten (10) two months patients with pulmonary tuberculosis therapy and ten (10) six months patients with pulmonary tuberculosis therapy and forty (40) apparently healthy individuals which served as control.Collected bloods were tested using Mindray chemistry analyzer lipid profiles.The mean serum levels of triglyceride, total cholesterol, high density lipoprotein and low-density lipoprotein were significantly lower than their respective control groups (p = 0.001).Pulmonary Tuberculosis patients in this study had lipid profile abnormalities.Total Cholesterol, HDL, LDL and TG concentrations were significantly reduced as compared with control groups.The factors associated with Lipid profiles also due attention to prevent further complication.This study concludes that parameters of lipid profile were deranged in our tuberculous cases.To achieve maximum response of TB treatment we must consider normalizing lipid profile along with standard treatment for better recovery.