OPTIMIZING THE TREATMENT OF DRUG-RESISTANT PULMONARY TB

Under the conditions of the tuberculosis epidemic that has developed in recent years, the course of tuberculosis infection and the structure of clinical forms have changed dramatically. Cases of a progressive course of this disease with an acute onset or an acute outbreak of the disease with massive bacterial excretion have become more frequent . The number of patients with primary drug resistance of mycobacterium tuberculosis increased sharply - from 18 to 37%. Modern pathomorphosis of tuberculosis led to a significant decrease in the effectiveness of chemotherapy. On average for In Uzbekistan, only 44.6% of newly diagnosed patients with a treatment period of 8-10 months. are discharged from the hospital with significant improvement (without decay in the lungs and bacterial excretion ), at the same time, the effectiveness of conservative treatment of patients with drug-resistant tuberculosis varies from 8 to 29%