TB Research

[Progress on the safety and efficacy of bedaquiline for the treatment of drug-resistant tuberculosis in special populations].

Y P Zhang, Yangyang Niu, Patrick Tang

PubMed · 2023-06

Abstract

is a serious threat to global tuberculosis(TB) control. WHO listed bedaquiline as one of the first-choice drugs for the treatment of MDR/RR-TB in 2018. Bedaquiline is marketed for adult patients with MDR-TB and XDR-TB. However, there are few studies of bedaquiline in adolescents, pregnant women, the elderly, and other special populations with drug-resistant TB. This paper aimed to review the effectiveness and safety of bedaquiline in the treatment of special populations of drug-resistant TB for the clinical use.

MeSH terms

  • Bedaquiline
  • Medicine
  • Tuberculosis
  • Drug resistance
  • Mycobacterium tuberculosis
  • Drug
  • Culture conversion
  • Multiple drug resistance
  • Internal medicine
  • Intensive care medicine