TB Research

The role of tuberculin skin test in BCG vaccination in Hilla city

Ahmed Hussein Jasim, Amjed Hikmet Alhasnawi, Hassan Salim Aljumaily

Zenodo (CERN European Organization for Nuclear Research) · 2023-05

Abstract

<strong>Introduction: </strong>Tuberculosis is currently one of the planet's most serious healthy issues. Search the effect of BCG vaccine on tuberculin skin test results. <strong>Patients and methods</strong>: From January 2018 to January 2019, 1109 patients were enrolled in the trial, which took place at the Tuberculosis Center in Babylon Province. Tuberculin skin testing was done using the mantoux method, which involved injecting 0.1 unit of pure tuberculin protein intradermally and reading the result after 48 hours (mm). <strong>Result:</strong> This cross-sectional revision of 1109 patients aged 1 to 85 years old in Babylon province who had BCG immunization at birth. Females outnumbered males in terms of percentage (52 percent versus 48 percent). The BCG vaccinated cases were 966 (87%) while the number of non-BCG vaccinated cases was 143 (13%). The quantity of tuberculin skin test diameters (0-5mm) are1007 (90.8%) patients in non-vaccinated patients 129 (12.8%) and vaccinated patients 878 (87.2%), diameter (6-10mm) 33 (3%) patients in non-vaccinated 6 (18.2%) and vaccinated 27 (81.8%) and tuberculin skin diameter (&gt; 11mm) 69 (6.2%) patients in non-vaccinated 8 (11.6%) and vaccinated patients 61 (88.1%). Vaccinated subjects had a larger skin test diameter than not received vaccine, and the difference was critical (p value=0.029). <strong>Conclusion</strong>: There is a statistically significant link between the BCG vaccine,positivity and the diameter of the tuberculin test.

MeSH terms

  • Tuberculin
  • Tuberculin test
  • Vaccination
  • Skin test
  • Medicine
  • Test (biology)
  • Dermatology
  • Immunology
  • Virology
  • Tuberculosis