TB Research

Comparison of metagenomic next-generation sequencing technology and GeneXpert MTB/RIF assay in tuberculosis:a meta-analysis

Jiadan Liao

Abstract

Review question / Objective: The research on the diagnostic value of mNGS and Xpert for tuberculosis is mainly based on small samples, and the results obtained are somewhat different.Therefore, the author conducts a meta-analysis of the literature on the accuracy of using mNGS and Xpert to diagnose tuberculosis, compares the application value of the two methods in the diagnosis of tuberculosis, and makes a comprehensive evaluation to provide reference for optimizing the clinical rapid diagnosis ability and strengthening treatment and management.Condition being studied: The author conducts a meta-analysis of the literature on the accuracy of using mNGS and Xpert to diagnose tuberculosis, compares the application value of the two methods in the diagnosis of tuberculosis.

MeSH terms

  • GeneXpert MTB/RIF
  • Tuberculosis
  • Medicine
  • Meta-analysis
  • Tuberculosis diagnosis
  • Metagenomics
  • Medical physics