New Onset of Tuberculosis Complicating FDG PET/CT Evaluation in Patient With Recent Chimeric Antigen Receptor T-Cell Therapy
Guanyun Wang, Xu Yang, Hongrong Wang, Wei Wang, Jigang Yang
Clinical Nuclear Medicine · 2023-04
Abstract
ABSTRACT: A 16-year-old adolescent girl with CD19 chimeric antigen receptor (CAR) T-cell therapy for acute lymphoblastic leukemia experienced new onset of the fever. 18 F-FDG PET/CT studies acquired at 1 and 2 months, respectively, after CAR-T, showed foci of abnormal activity in the mediastinal lymph nodes not seen on the study before therapy. However, these foci of abnormal activity were later proven due to newly developed tuberculosis after CAR T-cell therapy.
MeSH terms
- Medicine
- Chimeric antigen receptor
- Tuberculosis
- CD19
- Antigen
- Cell therapy
- T cell
- Immunology
- Cell
- Pathology