TB Research

Mycobacterium Tuberculosis Infection in AECOPD Combined with Pulmonary Embolism: a Case Report

Jing Bai, Qin Zhang, Jing Liu, Jing Wang, Qian Chen, Xin Zhou, Rong Liu, Shan Gao, et al. (10 authors)

Clinical Laboratory · 2023-01

Abstract

BACKGROUND: Mycobacterium tuberculosis belongs to the group of mycobacteria, most of which can cause a delayed hypersensitivity reaction in the body and is a bacterium that causes tuberculosis. Mycobacterium tuberculosis infection often presents with symptoms of tuberculosis toxicity and rarely with respiratory distress. At the same time, chest imaging often shows an ill-defined solid shadow in the apical and posterior segments of the upper lobe and, less frequently, in the dorsal segment of the lower lobe, and less frequently a diffuse nodular shadow. We report a case of AECOPD combined with pulmonary embolism infected with Mycobacterium tuberculosis. METHODS: Bronchoscopy, Next-generation sequencing (NGS). RESULTS: Antacid staining of bronchoalveolar lavage fluid suggested that a small amount of Mycobacterium antacid was visible. NGS was sent for examination and it suggested the presence of Mycobacterium tuberculosis with a sequence number of 5 (reference range ≥ 0). Treatment such as bronchodilation and antituberculosis was given. CONCLUSIONS: In patients with dyspnea, it is crucial to find the causative agent and to promptly improve relevant examinations such as pulmonary arteriography and bronchoscopy, and if necessary, to make a definitive diagnosis by NGS.

MeSH terms

  • Medicine
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Bronchoalveolar lavage
  • Bronchoscopy
  • Respiratory distress
  • Mycobacterium
  • Lung
  • Pathology
  • Internal medicine
  • Radiology