Estimation levels of interleukin-10 and interferon gamma in serum patients with tuberculosis in Iraq

This study was applied on 90 tuberculosis patients admitted in “the Babylon Center of Tuberculosis and Chest diseases in Hilla, Iraq”. They were divided into four groups; 50 patients with Pulmonary, 40 patients with Extra pulmonary,20 people as healthy contact group and 20 people as healthy control group. Blood samples were collected from patients and control group to estimate interferon gamma, and Interleukin-10 using the enzyme linked immunosorbent Assay technique. The ages range of all tuberculosis cases were ranged from 11 to more than 71 years; tuberculosis patients consisted of 51 males and 39 females. The interleukins-10 was at their highest levels in the group of Pulmonary and Extra pulmonary patients while the lowest levels were in the healthy control and contact group. The interferon gamma shows that the concentration in serum of the pulmonary tuberculosis patients was significantly lower than control and contact group while the concentration of interferon gamma in serum of the extra pulmonary tuberculosis patients was significantly higher than control and contact group.