Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques
Erica C. Larson, Amy Ellis, Mark A. Rodgers, Abigail K. Gubernat, Janelle L. Gleim, Ryan V. Moriarty, Alexis J. Balgeman, Yonne Karoline Tenório de Menezes, et al. (20 authors)
Infection and Immunity · 2023-04
Abstract
T cells were elevated. Thus, ART treatment of juvenile macaques, 3 months after SIV infection, resulted in similar progression of Mtb and T cell responses compared to Mtb in SIV-naive macaques.
MeSH terms
- Simian immunodeficiency virus
- Coinfection
- Tuberculosis
- Immunology
- Biology
- CD8
- Virology
- Mycobacterium tuberculosis
- Immune system
- Immunity
- Viral load
- Macaque
- Cytotoxic T cell
- Lentivirus
- T cell
- Virus