TB Research

Type 2 Diabetes Mellitus- and Complication-Related Risk of Nontuberculous Mycobacterial Disease in a South Korean Cohort

Da Som Jeon, Seon‐Ok Kim, Mi Ae Kim, Yong Pil Chong, Tae Sun Shim, Chang Hee Jung, Ye‐Jee Kim, Kyung‐Wook Jo

Microbiology Spectrum · 2023-03

Abstract

We assessed whether patients with T2DM are at higher risk for incident NTM disease through analysis of NTM-naive matched cohorts from the data of a national population-based cohort which represents 2.2% of the total South Korean population. Although T2DM alone is not a statistically significant risk factor for NTM disease, T2DM significantly increases the risk of NTM disease in those with ≥2 diabetes-related complications. This finding suggested that patients with T2DM with a larger number of complications should be considered a high-risk group for NTM disease.

MeSH terms

  • Medicine
  • Cohort
  • Hazard ratio
  • Population
  • Internal medicine
  • Cohort study
  • Type 2 Diabetes Mellitus
  • Diabetes mellitus
  • Nontuberculous mycobacteria
  • Incidence (geometry)
  • Risk factor
  • Disease
  • Confidence interval