TB Research

Diagnostic value of sputum cell count in severe asthma

J Kiesch, Pontus Mertsch, Carlo Mümmler, Nikolaus Kneidinger, John Behr, Katrin Milger

Pneumologie · 2023-03

Abstract

Background In severe asthma, blood eosinophil count (BEC) is used as standard biomarker for assessment of eosinophilic phenotype and eligibility for biologic therapies. However, patients with type-2 inflammation may have normal blood eosinophil levels e.g. due to corticosteroid therapy or spontaneous temporal variability.

MeSH terms

  • Eosinophil
  • Medicine
  • Sputum
  • Asthma
  • Biomarker
  • Eosinophilic
  • Immunology
  • Complete blood count
  • Blood count
  • Internal medicine