CRISPR-Based Detection, Identification and Typing of Mycobacterium tuberculosis Complex Lineages
Abdou Padane, Zelika Harouna Hamidou, Michel Drancourt, Jamal Saad
Microbiology Spectrum · 2023-01
Abstract
The whole-genome sequence comparison of the Mycobacterium tuberculosis complex (MTC) genomic sequences that are available in the NCBI database identified a unique, specific gene to be used directly on clinical diagnostic samples to detect MTC against all species of mycobacteria and to differentiate between MTC species, lineages, and sublineages.
MeSH terms
- Mycobacterium tuberculosis complex
- Tuberculosis
- Mycobacterium tuberculosis
- Nontuberculous mycobacteria
- Biology
- GeneXpert MTB/RIF
- Polymerase chain reaction
- Mycobacterium
- Typing
- Microbiology
- Virology