Disseminated mycobacterial infections after tumor necrosis factor inhibitor use, revealing inborn errors of immunity
Squire JD, Libertin CR, Powers H, Nelson J, Brumble L, Laham FR, Agharahimi A, Freeman AF, et al. (9 authors)
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023-04
Abstract
Tumor necrosis factor-a inhibitors can be associated with increased risk of infections, particularly reactivation of latent tuberculosis or nontuberculous mycobacterium (NTM). However, because disseminated NTM is rare, inborn errors of immunity should be considered. We present three patients with disseminated NTM after tumor necrosis factor-a inhibitor use who were found to have inborn errors of immunity.
MeSH terms
- Humans
- Tumor Necrosis Factor-alpha
- Mycobacterium Infections, Nontuberculous
- Nontuberculous Mycobacteria
- Tumor Necrosis Factor Inhibitors