TB Research

Clinical Features, Long-Term Outcomes, and Prognostic Factors of Eales' Disease in Korean Patients

Lee SM, Jung JH, Lee J, Choi EY, Shin JY, Kim M

Ocular immunology and inflammation · 2023-03

Abstract

Purpose We studied Korean patients with Eales' disease to document clinical features, long-term outcomes, and explore its association with TB, given South Korea's high TB burden. Methods We retrospectively reviewed medical records of Eales' disease patients for clinical characteristics, long-term outcomes, and its association with TB. Results Among 106 eyes, the average age of diagnosis was 39.28 years, with 82.7% male and 58.7% having unilateral involvement. Patients who underwent vitrectomy showed greater long-term improvement in visual acuity ( P = .047), while those with glaucoma filtration surgery showed less improvement ( P = .008). Having glaucoma through disease progression was associated with poor visual outcomes (odds ratio=15.556, P Conclusions In Korean patients with Eales' disease, we observed male predominance, unilateral presentation, older age of onset, and a link with TB. Timely diagnosis and management should be considered to maintain good vision in patients with Eales' disease.

MeSH terms

  • Humans
  • Tuberculosis, Ocular
  • Retinal Vasculitis
  • Neovascularization, Pathologic
  • Prognosis
  • Vitrectomy
  • Retrospective Studies
  • Follow-Up Studies
  • Visual Acuity
  • Adolescent
  • Adult
  • Aged
  • Middle Aged
  • Female
  • Male
  • Young Adult
  • Republic of Korea