TB Research

Intravitreal Anti-Vascular Endothelial Growth Factor and Moxifloxacin for Treatment of Tubercular Choroidal Granuloma and Sub retinal Abscess

Manoharan A, Mohan S, Raman R, Biswas J

Ocular immunology and inflammation · 2023-01

Abstract

Purpose To report the treatment response of a case of tubercular choroidal granuloma and subretinal abscess with intravitreal anti-vascular endothelial growth factor (anti-VEGF) and moxifloxacin. Method Retrospective interventional case report. Results A 34-year-old man presented with bilateral choroidal granuloma and subretinal abscess in one eye. He was a known case of spinal tuberculosis and was on anti-tubercular therapy. Patient was successfully treated with intravitreal injection of anti-VEGF and moxifloxacin. Conclusion Intravitreal anti-VEGF and moxifloxacin combination may be beneficial in tubercular choroidal granuloma and subretinal abscess.

MeSH terms

  • Humans
  • Eye Infections, Bacterial
  • Tuberculosis, Ocular
  • Abscess
  • Retinal Diseases
  • Choroid Diseases
  • Granuloma
  • Quinolines
  • Fluoroquinolones
  • Angiogenesis Inhibitors
  • Vascular Endothelial Growth Factor A
  • Antitubercular Agents
  • Tomography, Optical Coherence
  • Fluorescein Angiography
  • Drug Therapy, Combination
  • Retrospective Studies
  • Visual Acuity
  • Adult
  • Male
  • Intravitreal Injections
  • Bevacizumab
  • Ranibizumab
  • Moxifloxacin