[Contribution of the Xpert MTB / Rif test in the diagnosis of tuberculosis of any form in Saint-Louis].
S. Niang, Fbr Mbaye, M.F. Cissé, Dia Diatou Gueye, Émilia Ndiaye, Alioune Dièye, K H Thiam, Yaghouba Kane, et al. (10 authors)
PubMed · 2022-01
Abstract
INTRODUCTION: The Xpert MTB / RIF assay has a dual advantage on the one hand, the rapid diagnosis of even difficult cases by the standard technique of direct microscopic examination and on the other hand by the detection of resistance to rifampicin. Our objective was to determine the contribution of the Xpert test in the diagnosis of tuberculosis of all forms. MATERIALS AND METHOD: retrospective, descriptive and analytical study carried out in the Pneumophtisiology department of the CHRU of Saint-Louis. All suspected tuberculosis cases who had received an Xpert test from 2018 to 2020 were included. The parameters studied were socio-demographic, clinical and biological data. RESULTS: 524 patient records included in the study with a sex ratio of 1.3. The mean age of the patients was 37 +/-15 years. There were 285 positive GeneXpert samples, of which 224 were of pulmonary origin and 61 of extra-pulmonary origin. The number of rifampicin resistant samples was five, all of respiratory origin. CONCLUSION: the Xpert test is a new molecular technique recommended by the WHO in the diagnosis of pulmonary tuberculosis.
MeSH terms
- Medicine
- GeneXpert MTB/RIF
- Rifampicin
- Tuberculosis
- Pulmonary tuberculosis
- Pcr test
- Diagnostic test
- Surgery
- Mycobacterium tuberculosis