TB Research

Simultaneous clinical presentation of Vogt-Koyanagi-Harada disease and ocular tuberculosis

Raul E. Ruiz‐Lozano, I. Jocelyn Rivera-Alvarado, Luis A. Rodriguez-Gutierrez, Lucas A. Garza‐Garza, Alejandro Rodríguez-García

The Pan-American Journal of Ophthalmology · 2022-01

Abstract

The simultaneous occurrence of an infectious and an autoimmune systemic disorder associated with bilateral panuveitis is always feasible but improbable. While Vogt-Koyanagi-Harada requires prompt systemic corticosteroids and immunosuppressives, ocular tuberculosis (TB) requires multiple antibiotic therapies, and to a certain extent, corticosteroids to avoid inflammatory damage to crucial intraocular structures. We report a patient with granulomatous bilateral panuveitis, in which VKH and ocular TB were diagnosed simultaneously. This case emphasizes the importance of ruling out TB in the presence of a granulomatous panuveitis, despite the lack of pulmonary manifestations, especially in an endemic country. The hindmost because both diseases require different treatments.

MeSH terms

  • Medicine
  • Vogt–Koyanagi–Harada disease
  • Tuberculosis
  • Dermatology
  • Uveitis
  • Presentation (obstetrics)
  • Disease
  • Sarcoidosis
  • Ophthalmology
  • Immunology