Predictors of anxiety depression disorders during active pulmonary tuberculosis

<b>Introduction:</b> Tuberculosis is a global public health problem. It affects the quality of life with a significant psychological impact. The aim of this study is to determine the prevalence and predictors of anxiety and depression in patients with active tuberculosis. <b>Methods:</b> A prospective study using a predefined Hospital Anxiety and Depression Scale (HAD) questionnaire conducted in pneumology “C”department of Mami Ariana Tunisia hospital, between January 2020 and February 2022. Two groups were compared: G1 (normal or borderline mood, n=45) and G2 (anxious or depressed, n=48). Patients with a psychiatric history were not included. <b>Results:</b> One hundred and fifty patients were questioned. Ninety-three answered (62%). Mean age was 44 years. The sex ratio was1.38. Fourty eight (51.6%) patients had an anxiety-depressive syndrome. The mean HAD score was 12 [3-28]. Smoking intoxication was more frequent and greater in G2: [65% of smokers in G2 versus 34% in G1; p: 0.04]. Comorbidities such as diabetes and high blood pressure were more noted in G2. Acute respiratory failure was greater in patients in group G2. We found a statistically significant relationship between the extent of tuberculosis lesions, delay in sputum negativation and the severity of the anxiety-depressive syndrome (p: 0.002). <b>Conclusion:</b> The prevalence of anxiety and depression is quite high in patients with tuberculosis, especially in severe forms. Screening for these disorders is essential to improve patient care.