TB Research

Editorial: Host immune evasion by Mycobacterium tuberculosis: Current updates

Meseret Habtamu, Adane Miheret, Anne Spurkland

Frontiers in Immunology · 2022-12

Abstract

Mycobacterium tuberculosis (M. tb) can become a long-term infection by evading the host's immune response. Virulent mycobacterial strains employ various strategies to hijack the host's immune systems in favor of persistent infection and disease progression. Although the immune evasion mechanisms identified so far are already numerous, they most likely represent only the tip of the iceberg. Identifying fundamental pathogen virulence regulators and investigating the underlying immune mechanisms remain critical in the quest for more effective vaccines and therapeutic targets.

MeSH terms

  • Evasion (ethics)
  • Mycobacterium tuberculosis
  • Immune system
  • Host (biology)
  • Tuberculosis
  • Host response
  • Immunology
  • Biology
  • Microbiology
  • Medicine