Repurposing Tamoxifen as Potential Host-Directed Therapeutic for Tuberculosis
Ralf Boland, Matthias T. Heemskerk, Gabriel Forn‐Cuní, Cornelis J. Korbee, Kimberley V. Walburg, Jeroen J. Esselink, Carina Carvalho dos Santos, Amy M. de Waal, et al. (17 authors)
mBio · 2022-12
Abstract
Tuberculosis (TB) is the world's most lethal infectious disease caused by a bacterial pathogen, Mycobacterium tuberculosis . This pathogen evades the immune defenses of its host and grows intracellularly in immune cells, particularly inside macrophages.
MeSH terms
- Tuberculosis
- Pathogen
- Mycobacterium tuberculosis
- Immune system
- Repurposing
- Infectious disease (medical specialty)
- Host (biology)
- Microbiology
- Virology
- Biology
- Immunology
- Disease
- Medicine