TB Research

Increasing Use Of Interferon Gamma Release Assays Among Children ≥2 Years of Age in a Setting With Low Tuberculosis Prevalence

Jeffrey I. Campbell, Mary Tabatneck, Mingwei Sun, Wei He, Nicholas Musinguzi, Bethany Hedt‐Gauthier, Gabriella S Lamb, Don Goldmann, et al. (11 authors)

The Pediatric Infectious Disease Journal · 2022-10

Abstract

US guidelines recommend interferon gamma release assays (IGRAs) for diagnosis of tuberculosis infection in children. In this retrospective cohort study, IGRA use in children 2-17 years of age increased substantially between 2015 and 2021. Testing in inpatient/subspecialty settings (vs. primary care), public (vs. private) insurance, lower age and non-English preferred language were associated with increased odds of receiving an IGRA.

MeSH terms

  • Medicine
  • Tuberculosis
  • Retrospective cohort study
  • Interferon gamma release assay
  • Odds
  • Cohort
  • Odds ratio
  • Pediatrics
  • Subspecialty
  • Mycobacterium tuberculosis
  • Family medicine
  • Internal medicine
  • Immunology