TB Research

ODP589 Acute Hypercalcemic Crisis in an Elderly with Granulomatous Disease

Maria Leonora Capellan, Leo Tiu

Journal of the Endocrine Society · 2022-11

Abstract

Abstract We present here a case of an 81 year old female who developed changes in neurologic status due to elevated serum calcium levels in the setting of an elevated Vitamin D and low-normal parathyroid hormone level. Upon evaluation of PTH-independent causes of hypercalcemia, she was noted to have Tuberculosis. Anti-Koch's and steroids were initiated on top of vigorous hydration and diuresis which lead to improvement in the patient's serum calcium levels and clinical status. Tuberculosis rarely leads to clinically significant hypercalcemia. However, elderly patients remain predisposed due to advanced age, multiple comorbidities and polypharmacy. Hypercalcemia is a life threatening condition, but with prompt diagnosis and management it portends excellent outcomes. Presentation: No date and time listed

MeSH terms

  • Medicine
  • Polypharmacy
  • Disease
  • Tuberculosis
  • Parathyroid hormone
  • Vitamin D and neurology
  • Diuresis
  • Miliary tuberculosis
  • Pediatrics
  • Internal medicine
  • Calcium