Pulmonary tuberculosis Biomarker discovery in the quest for new therapies

lobally, tuberculosis (TB) from infection with Mycobacterium tuberculosis (MtB) causes more deaths than any other bacterial infectious disease. TB is highly prevalent in low-and middle-income countries and patients with active TB may present with fever, weight loss, and tiredness. Current treatments either directly target and kill MtB or they amplify immune-response mechanisms to fight the infection. However, treatments are not fully effective and new treatments as well adjunctive therapies (those that complement existing treatments) are needed.