TB Research

REMOVED: Adverse pregnancy outcomes after in vitro fertilization due to undiagnosed urogenital tuberculosis and proposed screening algorithm for patients from tuberculosis-endemic countries

Stephanie E. McLaughlin, Surabhi B Vora, Elizabeth Church, Christopher Spitters, Angela Thyer, Sylvia M. LaCourse, Christopher N. Herndon

F&S Reports · 2022-08

Abstract

Objective: To report 2 cases of adverse pregnancy outcomes due to delayed diagnosis of urogenital tuberculosis and propose a screening algorithm for patients from tuberculosis-endemic countries. Design: Case report. Setting: Academic medical center. Patients: Two patients with delayed diagnosis of urogenital tuberculosis leading to a fetal loss and a preterm delivery of an infant with congenital tuberculosis. Interventions: Endometrial biopsy, acid-fast bacilli culture of urine, and endometrium. Main outcome measures: Pregnancy outcomes. Results: Fetal loss at 19 weeks and preterm delivery of an infant with congenital tuberculosis before urogenital tuberculosis treatment. Conclusions: Patients who are at risk of urogenital tuberculosis should be screened in advance of infertility treatment to potentially prevent adverse pregnancy outcomes.

MeSH terms

  • Medicine
  • Tuberculosis
  • Pregnancy
  • Genitourinary system
  • Obstetrics
  • Infertility
  • Adverse effect
  • Pediatrics