[Sources of <i>Klebsiella pneumoniae</i> Isolated in a Hospital in the Past Decade and Trends and Changes of <i>in vitro</i> Drug Susceptibility].

Objective: drug susceptibility, and to provide clinical references for the treatment of KP-associated infection. Methods: susceptibility to antimicrobial agents of KP isolated from clinical specimens in a hospital between January 2012 and December 2021 were retrospectively analyzed. Resistance rate of the extended-spectrum β-lactamases-producing isolates vs. that of the non-enzyme-producing ones, and the resistance rate of imipenem-resistant strains vs. that of imipenem-susceptible ones were compared and analyzed. Carbapenase inhibitor enhancement test was used to identify the types of the carbapenemases. Results: <0.05). Serine carbapenase-producing strains accounted for 91.1% (920/1010). Conclusion: drug susceptibility and the type of the carbapenemases of the isolates in order to provide guidance for the clinical usage of antibiotics.