TB Research

Peculiarities of Pleurisy in HIV-infected subjects at Jamot Hospital in Yaounde: Epidemiological, Clinical and Evolutionary Aspects

Claire Françoise Bitchong Ekono, Thérèse Azoumbou Mefant, Vanessa Essoh Kambo TongueMoujongue, Vanessa Linda Ngatcha Yoppa, E. Afane Ze

The Journal of Medical Research · 2022-05

Abstract

Introduction: The aim of this work was to highlight the particularities of pleurisy in HIV-infected subjects. Methods: This prospective, cross-sectional and comparative study was carried out from December 1, 2018to May 31, 2019 at Jamot Hospital in Yaoundé – Cameroon. Patients aged 18 and over with pleurisy were split into two groups, HIV + and HIV –. Epidemiological, clinical and evolutionary data were collected. The results were analyzed using SPSS version 20 software. Results: The size of our study population was 110 patients, to say 41 (37.3%) HIV positive and 69 (62.7%) HIV negative. The mean age was 39.66 ±1.14 years in the HIV + group and 46.8 ±2.20 years in the HIV - group. A history of tuberculosis was more common in HIV+; 24.4% against 8.7%; P=0.01. The general signs were more marked in the HIV+ group: weight loss (90.2% versus 44.9%; P <0.05) and excessive nocturnal sweating (61% versus 29%; P <0.05). Pneumothorax associated with pleurisy was more frequent in HIV+, non-significant difference (12.2 versus 8.7%; P= 0.55). Tuberculous etiology was more common in HIV+; P=0. The death rate was 17% in the HIV+ group versus 5.8%; P= 0.01. Conclusion: During HIV, pleurisy occurs at a younger age; the general signs are more marked than the respiratory signs. Tuberculosis causes and mortality are higher.

MeSH terms

  • Medicine
  • Pleurisy
  • Tuberculosis
  • Epidemiology
  • Etiology
  • Pneumothorax
  • Human immunodeficiency virus (HIV)
  • Internal medicine
  • Population
  • Prospective cohort study
  • Pediatrics
  • Surgery