Whole-Genome Sequencing for Resistance Level Prediction in Multidrug-Resistant Tuberculosis
Jinli Li, Tingting Yang, Chuangyue Hong, Zheng Yang, Likai Wu, Qian Gao, Hui Yang, Weiguo Tan
Microbiology Spectrum · 2022-06
Abstract
gene may be associated with this phenotype. Our data on the MIC distribution of strains with some rarer mutations add to the accumulated data on the resistance level associated with such mutations to help guide further research and draw meaningful conclusions.
MeSH terms
- rpoB
- Rifabutin
- Biology
- Rifampicin
- Drug resistance
- Genetics
- Mycobacterium tuberculosis
- Whole genome sequencing
- Multiple drug resistance
- Isoniazid
- Tuberculosis
- Genome
- Gene