Delayed HIV treatment, barriers in access to care and mortality in tuberculosis/HIV co-infected patients in Cali, Colombia.
Jorge A González-Duran, Regina Victoria Plaza, Lucy Luna, María Patricia Arbeláez, Meagan Deviaene, Yoav Keynan, Zulma Vanessa Rueda, Diana Marín
PubMed · 2022-05
Abstract
Objective: To determine factors associated with mortality in tuberculosis/HIV co-infected patients in Cali, Colombia. Methods: This retrospective cohort design included tuberculosis/HIV co-infected persons. Kaplan-Meier and Cox regression were used to estimate survival and risk factors associated with mortality. Results: , initiation of tuberculosis treatment within two weeks, having any health insurance coverage and CD4 count information conferred a survival advantage. Conclusions: Delays in treatment initiation and factors associated with limited health care access or utilization were associated with mortality. As HIV and tuberculosis are both reportable conditions in Colombia, strategies should be focused on optimizing treatment outcomes within both tuberculosis and HIV programs, particularly improving early HIV diagnosis, early antiretroviral therapy treatment initiation, and adherence to tuberculosis treatment.
MeSH terms
- Tuberculosis
- Medicine
- Proportional hazards model
- Retrospective cohort study
- Human immunodeficiency virus (HIV)
- Cohort
- Internal medicine
- Mycobacterium tuberculosis
- Immunology