Sensitivity of <i>Mycobacterium leprae</i> to Telacebec
Ramanuj Lahiri, Linda B. Adams, Sangeeta Susan Thomas, Kévin Pethe
Emerging infectious diseases · 2022-02
Abstract
Abstract The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis. The unprecedented potency of Telacebec against M. leprae warrants further validation in clinical trials.
MeSH terms
- Mycobacterium leprae
- Leprosy
- Mycobacterium tuberculosis
- Tuberculosis
- Microbiology
- Biology
- Potency
- Mycobacterium
- Virology
- Computational biology
- Medicine