TB Research

The comparative analysis of the drug resistance of mbtin children, adolescents and the sources of infection in the multidrug resistant tuberculosis focies

Olha Sakhelashvili-Bil, M.І. Sakhelashvili

Bulletin of the Academy of Sciences of Moldova Medical Sciences · 2022-01

Abstract

145 patients (67 children and 78 adolescents) from the multidrug-resistant tuberculosis infection focies took part in the complex microbiological study. The children and adolescents had undergone treatment for the pulmonary multidrugresistant tuberculosis. The study showed that MDR TB was by 1.7 times more often revealed in the adolescents as compared to the children, while the risk of MDR TB was by 3.7 times higher for the children than for the adolescents. The drug resistance profile of the children and the sources of infection almost completely coincided. The resistance to HRSE (66.1%) and HRESZ (13.6%) developed in the adolescents more often than in the children and adults. The study proves the importance of defining the drug resistance profile in the exposed children and adolescents from the multidrugresistant tuberculosis focies.

MeSH terms

  • Tuberculosis
  • Medicine
  • Multiple drug resistance
  • Drug resistance
  • Drug
  • Pediatrics
  • Pulmonary tuberculosis