Clinical, and Diagnostic Characteristics of an Unsuspected Course of Urinary Tuberculosis: A Brief Report

Human Tuberculosis caused by Mycobacterium tuberculosis (MTb) remains a serious public health problem because of the high percentage of asymptomatic infection. Even worse, from this percentage, around 20% develop disseminated Tuberculosis involving the urinary tract. How to approach this?. A key issue is the accuracy and speediness of the diagnosis. In the present brief report, we described and pinpointed an unsuspected course of urinary Tuberculosis in an individual that presented signs not very characteristic of non pulmonary TB. The main symptoms were microhematuria, urinary incontinence, and urinary infections. To gain insight into the characterization of the clinical manifestations of the infectious disease, we pursued unconventional analysis assays, along with classic microbiological media tools. Molecular (microarrays, pattern of biomarkers) and serological reactivity (mycobacterial antigens detection) were determined in both blood and exudates. Remarkably, in the urinary diagnosis of Tuberculosis, these alternative tools could provide strong support and input to the clinics, especially in unsuspected cases.