Caregiver willingness to give TPT to children living with drug-resistant TB patients
Rouzier V, Murrill M, Kim S, Naini L, Shenje J, Mitchell E, Raesi M, Lourens M, et al. (17 authors)
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022-10
Abstract
BACKGROUND Pediatric household contacts (HHCs) of patients with multidrug-resistant TB (MDR-TB) are at high risk of infection and active disease. Evidence of caregiver willingness to give MDR-TB preventive therapy (TPT) to children is limited. METHODS This was a cross-sectional study of HHCs of patients with MDR-TB to assess caregiver willingness to give TPT to children aged RESULTS Of 743 adult and adolescent HHCs, 299 reported caring for children aged CONCLUSIONS A high percentage of caregivers living with MDR- or rifampicin-resistant TB patients were willing to give children a hypothetical MDR TPT. These results provide important evidence for the potential uptake of effective MDR TPT when implemented.
MeSH terms
- Humans
- Tuberculosis, Multidrug-Resistant
- Rifampin
- Antitubercular Agents
- Cross-Sectional Studies
- Family Characteristics
- Adolescent
- Adult
- Child
- Caregivers
- Female
- Male