TB Research

IMPACT OF NUTRITIONAL CORRECTION OF PROTEIN METABOLISM DISORDERS ON THE CLINICAL COURSE OF PULMONARY TUBERCULOSIS

Galan IO, Protsyuk RG, Omelchuk ST, Yeltsova LB, Bondarenko YV, Galan AV

Wiadomosci lekarskie (Warsaw, Poland : 1960) · 2022-01

Abstract

Objective The aim: To study the impact of nutritional correction of protein metabolism disorders on the clinical course of pulmonary tuberculosis. Patients and methods Materials and methods: The study involved 67 patients with pulmonary tuberculosis, which were divided into two groups: group I - 35 patients who underwent nutritional correction of protein metabolism disorders against the background of antimycobacterial therapy (AMBT) and group II - 32 patients who received standard AMBT. An assessment of clinical indicators and the condition of protein metabolism (PM) was conducted by determining the concentration of individual non-essential, essential amino acids and their total amount. Results Results: The proposed correction scheme includes food products containing essential nutrients and biologically active compounds that have a positive impact on the corresponding links of pathogenesis and can be used throughout all phases of treatment. Its application had a positive impact on the indicators of PM (significant (p Conclusion Conclusions: The application of nutritional correction of protein metabolism in the complex treatment of patients with pulmonary tuberculosis made it possible to obtain a pronounced positive impact on the clinical course of the disease and the condition of protein metabolism, which contributed to an increase in the effectiveness of treatment and rehabilitation.

MeSH terms

  • Humans
  • Tuberculosis
  • Tuberculosis, Pulmonary
  • Metabolic Diseases
  • Amino Acids, Essential