TB Research

Prevalence and Drug Resistance Pattern of <i>Mycobacterium tuberculosis</i> Isolated from Tuberculosis Patients in Basra, Iraq

Mohammed KAS, Khudhair GS, Al-Rabeai DB

Polish journal of microbiology · 2022-05

Abstract

Drug-resistant Mycobacterium tuberculosis (DR-MTB) is a major health threat to human beings. This study aimed to evaluate the prevalence and drug resistance profile of MTB. Data were collected from 2,296 newly diagnosed, and 246 retreated tuberculosis (TB) patients who attended the Advisory Clinic for Chest Diseases and Respiratory in Basra province from January 2016 to December 2020. Both new diagnostic and retreated TB cases showed that DR-MTB cases were significantly higher at age 15-34 years, pulmonary TB, and urban residents but with no significant difference regarding gender. The drugs resistance was significantly higher among the retreated cases compared with the new diagnostic patients (20.3% vs. 2.4%, p M. tuberculosis since 2016, with a predominant multi-drug-resistant TB and isoniazid-resistant TB.

MeSH terms

  • Humans
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Tuberculosis, Multidrug-Resistant
  • Ethambutol
  • Isoniazid
  • Rifampin
  • Streptomycin
  • Antitubercular Agents
  • Prevalence
  • Drug Resistance, Multiple, Bacterial
  • Adolescent
  • Adult
  • Iraq
  • Young Adult