The association of cytokine gene polymorphisms with tuberculosis susceptibility in several regional populations

Purpose By collecting the data of all relevant articles, the goal of this study was to better understand the relationship between the IL-6/IL-18 polymorphism and susceptibility to tuberculosis in several regional populations. Methods Pubmed, Embase, WOS and CNKI were used to find relevant literature. The findings of separate research were merged using Review Manager. Results A total of 25 studies were included in this study. IL-6 rs1800795 (dominant. comparison: p-value Conclusion This meta-analysis found that the the IL-6 rs1800795and IL-18 rs187238 polymorphisms may have a role in TB susceptibility.