Clinical characteristics of COVID-19 in patients with tuberculosis and factors associated with the disease severity
Parolina L, Pshenichnaya N, Vasilyeva I, Lizinfed I, Urushadze N, Guseva V, Otpushchennikova O, Dyachenko O, et al. (9 authors)
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022-04
Abstract
Background Data on patients with COVID-19 who have pulmonary tuberculosis (TB) are limited. In this study, we compared the clinical characteristics of patients with COVID-19/TB and patients with COVID-19 only. In addition, we analyzed the links between the severity of COVID-19 disease and the clinical characteristics of patients with COVID-19/TB. Methods We conducted a retrospective, anonymized, cross-sectional study of 111 patients who met inclusion criteria for analysis (75 patients with COVID-19/TB and 36 patients with COVID-19). Results Patients in both groups (COVID-19/TB vs COVID-19) mainly suffered from fever (72.0% vs 100%, p Conclusion It is important to perform rapid molecular testing and computed tomography to correctly distinguish COVID-19 and TB because of the similar clinical characteristics of both diseases. Bilateral pulmonary TB lesion and co-morbidity should be considered risk factors for severe COVID-19.
MeSH terms
- Humans
- Tuberculosis
- Tuberculosis, Pulmonary
- Fever
- Retrospective Studies
- Cross-Sectional Studies
- Female
- Patient Acuity
- COVID-19