Case Report: Isoniazid-Associated Delirium in an Elderly Female with Spinal Tuberculosis

Isoniazid is an important component of first-line antitubercular therapy. The drug at its therapeutic dose is known to cause hepatitis and peripheral neuropathy. The association of isoniazid with pure delirium is rare. Here, we present an interesting case of new-onset delirium associated with isoniazid in an elderly female with spinal tuberculosis. Remarkable improvement was noticed in the patient following drug discontinuation and pyridoxine augmentation.