TB Research

Incidence and Mortality of Extrapulmonary Tuberculosis in Ukraine: Analysis of National Surveillance Data

Khalife S, Jenkins HE, Dolynska M, Terleieva I, Varchenko I, Liu T, Carter EJ, Horsburgh CR, et al. (11 authors)

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022-09

Abstract

Background Improved understanding of the epidemiology and mortality risk factors of extrapulmonary tuberculosis (EPTB) may facilitate successful diagnosis and management. Methods We analyzed national surveillance data from Ukraine to characterize EPTB subtypes (ie, localized in different anatomic sites). We calculated annual reported incidence, stratified by age, sex, and human immunodeficiency virus (HIV) status. Using Cox regression, we estimated mortality risk factors. Results Between January 2015 and November 2018, 14 062 adults/adolescents (≥15 years) and 417 children ( Conclusions We identified the most common EPTB subtypes by age and sex, patterns of EPTB disease by HIV status, and mortality risk factors. These findings can inform diagnosis and care for people with EPTB.

MeSH terms

  • Humans
  • Tuberculosis
  • Tuberculosis, Pulmonary
  • HIV Infections
  • Incidence
  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Ukraine
  • Male