Evaluation of Cytological Changes among Smoker Patients with Pulmonary Tuberculosis

Background: Pulmonary Tuberculosis (TB) is a major public health concern worldwide: despite a regular, although slow, decline in incidence over the last decade. Therefore, the aim of this study was to evaluate cytological change of sputum in smoker patients with TB. Methodology: A total of 200 sputum samples (100smoker patients were ZN stain positive (case) and 100 patients were Zn negative). Data were collected by questionnaire and the collected sputum smear were subjected to Papanicolaou stain and microscopically analyzed for studying cytological alterations. Results: The cytological finding of the case groups was as follows 28% reported with chronic inflammatory changes, 64% micro nuclear changes, 8% metaplastic changes, P. value was 0.00, there were significant with TB patients. Conclusion: significant changes in sputum sample associated smoker Patients with TB that requires further consideration.