Tuberculosis Presenting as Thrombotic Thrombocytopenic Purpura
Anu Maheshwari, Vikram Bhaskar, Krishanu Mondal, Anju Seth
Indian Pediatrics Case Reports · 2021-01
Abstract
Background: Thrombotic thrombocytopenic purpura (TTP) is a rare disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure, and central nervous system impairment. Clinical Description: Although most cases of TTP are idiopathic, there are some case reports describing its association with certain infections. We report a rare case of TTP associated with tuberculosis which was confirmed by ADAMTS13 levels. Management: This child was managed with high-dose plasma infusion. Conclusion: To the best of our knowledge, this is the first case in a pediatric patient with this association and treated successfully by high-dose plasma infusion.
MeSH terms
- Thrombotic thrombocytopenic purpura
- Medicine
- Microangiopathic hemolytic anemia
- Purpura (gastropod)
- Thrombocytopenic purpura
- Tuberculosis
- Hemolytic anemia
- Pediatrics
- Dermatology
- Internal medicine