TB Research

Tuberculosis Presenting as Thrombotic Thrombocytopenic Purpura

Anu Maheshwari, Vikram Bhaskar, Krishanu Mondal, Anju Seth

Indian Pediatrics Case Reports · 2021-01

Abstract

Background: Thrombotic thrombocytopenic purpura (TTP) is a rare disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure, and central nervous system impairment. Clinical Description: Although most cases of TTP are idiopathic, there are some case reports describing its association with certain infections. We report a rare case of TTP associated with tuberculosis which was confirmed by ADAMTS13 levels. Management: This child was managed with high-dose plasma infusion. Conclusion: To the best of our knowledge, this is the first case in a pediatric patient with this association and treated successfully by high-dose plasma infusion.

MeSH terms

  • Thrombotic thrombocytopenic purpura
  • Medicine
  • Microangiopathic hemolytic anemia
  • Purpura (gastropod)
  • Thrombocytopenic purpura
  • Tuberculosis
  • Hemolytic anemia
  • Pediatrics
  • Dermatology
  • Internal medicine