TB Research

1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis

Lutete Peguy Khonde, Rudolf Müller, Grant A. Boyle, Virsinha Reddy, Aloysius T. Nchinda, Charles J. Eyermann, Stephen E. Fienberg, Vinayak Singh, et al. (24 authors)

Zenodo (CERN European Organization for Nuclear Research) · 2021-08

Abstract

This is the accepted manuscript version of the work published in its final form as Khonde, Lutete Peguy; Müller, Rudolf; Boyle, Grant A.; Reddy, Virsinha; Nchinda, Aloysius T.; Eyermann, Charles J.; Fienberg, Stephen; Singh, Vinayak; Myrick, Alissa; Abay, Efrem; Njoroge, Mathew; Lawrence, Nina; Su, Qin; Myers, Timothy G.; Boshoff, Helena I. M.; Barry, Clifton E.; Sirgel, Frederick A.; van Helden, Paul D.; Massoudi, Lisa M.; Robertson, Gregory T.; Lenaerts, Anne J.; Basarab, Gregory S.; Ghorpade, Sandeep R.; Chibale, Kelly. Journal of Medicinal Chemistry Volume: 64 issue: 17, page(s): 12790–12807. https://doi.org/10.1021/acs.jmedchem.1c00837 Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailing help@openaccessbutton.org.

MeSH terms

  • Mycobacterium tuberculosis
  • Tuberculosis
  • Biosynthesis
  • Microbiology
  • Cell wall
  • Mycobacterium
  • Virology
  • Biology
  • Medicine